Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952850 | 0.85 | CYP3A4 (0.44) | TAAR1TSHRMAPK1FOSTTR | |
| SCHEMBL3081718 | 0.82 | SLC6A4 (0.50) | MAPK1LMNAALDH1A1TDP1 | |
| SCHEMBL1039963 | 0.82 | REN (0.48) | TDP1 | |
| SCHEMBL3979694 | 0.82 | TSHR (0.41) | TSHRTTRLMNAALDH1A1TDP1 | |
| SCHEMBL3977128 | 0.81 | L3MBTL1 (0.43) | MAPK1LMNAGLAALDH1A1CYP3A4 | |
| SCHEMBL3977294 | 0.81 | L3MBTL1 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL6044572 | 0.80 | KDM4E (0.46) | LMNAALDH1A1ARSMPD1ALOX15 | |
| SCHEMBL3077526 | 0.79 | BIRC5 (0.47) | TSHRMAPK1LMNAALDH1A1CYP3A4 | |
| SCHEMBL4743467 | 0.79 | L3MBTL1 (0.41) | — | |
| SCHEMBL5443737 | 0.79 | TAAR1 (0.65) | TAAR1TSHRMAPK1FOSTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024772-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-03-04 | — | — | WO | disclosed |