SCHEMBL3977652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3977724	0.83	NPC1 (0.50)	MEN1KMT2AALDH1A1SMN1; SMN2MAPT
	SCHEMBL3982429	0.81	TOP1 (0.44)	MEN1KMT2AMAPTNPC1RAB9A
	SCHEMBL3981613	0.81	CCNC (0.42)	MEN1KMT2AALDH1A1SMN1; SMN2MAPT
	SCHEMBL3983962	0.78	MEN1 (0.40)	MEN1KMT2AMAPTNPC1RAB9A
	SCHEMBL3982131	0.78	KMT2A (0.40)	MEN1KMT2ALMNAALDH1A1NPC1
	SCHEMBL3983192	0.78	ESR1 (0.41)	MEN1KMT2AKDM4ELMNANPC1
	SCHEMBL3973507	0.78	MEN1 (0.40)	MEN1KMT2AALDH1A1SMN1; SMN2MAPT
	SCHEMBL3981075	0.78	MEN1 (0.40)	MEN1KMT2AKDM4EHTTLMNA
	SCHEMBL3976756	0.78	ACLY (0.40)	KDM4EALDH1A1NPC1RAB9ATDP1
	SCHEMBL3976138	0.77	RAB9A (0.50)	MEN1KMT2AHTTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.