SCHEMBL3978058

SCHEMBL3978058

Cc1nnc(C(=O)O)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL30570038 0.98 L3MBTL1 (0.42)
SCHEMBL29067361 0.98 L3MBTL1 (0.42)
SCHEMBL7020662 0.81 DAO (0.35)
Hydrochloric Acid SCHEMBL11595879 0.78 GPR35 (0.33)
SCHEMBL490429 0.78
SCHEMBL18364468 0.77 ALDH1A1 (0.38)
Lithium Ion SCHEMBL29067359 0.76 L3MBTL1 (0.37)
SCHEMBL19300250 0.75 SMN1; SMN2 (0.41)
SCHEMBL28858878 0.74
SCHEMBL8217774 0.73 SMN1; SMN2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3833672-B1 TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS OSPEDALE SAN RAFFAELE SRL (IT) 2024-09-18 EP disclosed
CN-113272309-B Tricyclic inhibitors of hepatitis b virus 圣拉斐尔医院有限公司 2024-02-23 CN disclosed
US-20230250060-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 US disclosed
US-20230076319-A1 INHIBITORS OF HEPATITIS B VIRUS ANTIOS THERAPEUTICS INC (US) 2023-03-09 US disclosed
US-11504382-B2 Tricyclic inhibitors of Hepatitis B virus Antios Therapeutics, Inc. (US) 2022-11-22 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20220110943-A1 TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS OSPEDALE SAN RAFFAELE S.R.L. (IT) 2022-04-14 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
CN-113272309-A Tricyclic inhibitors of hepatitis B virus 圣拉斐尔医院有限公司 2021-08-17 CN disclosed
EP-3833672-A1 TRICYCLIC INHIBITORS OF HEPATITIS B VIRUS Ospedale San Raffaele S.r.l. (IT) 2021-06-16 EP disclosed
US-7510605-B2 Dye ink, ink jet recording method, ink sheet, color toner and color filter FUJIFILM CORPORATION (JP) 2009-03-31 US disclosed
US-7510605-B2 Dye ink, ink jet recording method, ink sheet, color toner and color filter FUJIFILM CORPORATION (JP) 2009-03-31 US disclosed
US-7507282-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-20080287466-A1 4-AMINO-2,3-DISUBSTITUTED THIENO [2,3,D]PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF ADAMS JERRY LEROY 2008-11-20 US disclosed
US-7427623-B2 4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof SMITHKLINE BEECHAM CORPORATION (US) 2008-09-23 US disclosed
US-20080199615-A1 Dye, Ink, Ink Jet Recording Method, Ink Sheet, Color Toner and Color Filter FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080199615-A1 Dye, Ink, Ink Jet Recording Method, Ink Sheet, Color Toner and Color Filter FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20050004142-A1 Chemical compounds SMITHKLINE BEECHAM CORPORATION 2005-01-06 US disclosed
EP-1425284-A2 FURO- AND THIENOPYRIMIDINE DERIVATIVES AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2004-06-09 EP disclosed
WO-2003022852-A2 FURO-AND THIENOPYRIMIDINE DERIVATIVES AS ANGIOGENESIS INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2003-03-20 WO disclosed