SCHEMBL3978482

SCHEMBL3978482

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)c1c(F)cc(F)cc1F

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.37
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
PPARD Q03181 1/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
SOAT1 P35610 1/20 0.34
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21519517 0.78 DNM1 (0.38) DNM1CNR2
SCHEMBL5715845 0.77 SOAT1 (0.39) PPARGPPARAPPARDSOAT1CNR2
SCHEMBL5082545 0.75 DNM1 (0.42) DNM1THRBCNR2
SCHEMBL21519592 0.75 DNM1 (0.42) DNM1THRBCNR2
SCHEMBL5088802 0.75 DNM1 (0.42) DNM1THRBCNR2
SCHEMBL29002046 0.75 DNM1 (0.42) DNM1THRBCNR2
SCHEMBL3978473 0.75 DNM1 (0.42) DNM1THRBCNR2
SCHEMBL5715939 0.74 CNR2 (0.40) PPARGPPARAPPARDSOAT1CNR2
SCHEMBL5716608 0.74 DNM1 (0.41) DNM1THRB
Hydrochloric Acid SCHEMBL29002048 0.74 DNM1 (0.44) DNM1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299405-B1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2009-05-13 EP claimed
US-6800701-B2 USING COORDINATION CATALYSTS DOW GLOBAL TECHNOLOGIES INC. 2004-10-05 US claimed
US-20030216529-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2003-11-20 US claimed
EP-1299405-A1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-04-09 EP claimed
US-20020062011-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2002-05-23 US claimed
WO-2002002577-A1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGY INC. (US) 2002-01-10 WO claimed
EP-1299405-B1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2009-05-13 EP disclosed
EP-1487886-B1 SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2008-08-06 EP disclosed
US-20080051531-A1 GAS PHASE PROCESS FOR POLYMERS WITH GROUP 4 METAL COMPLEX CATALYST ADDITION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2008-02-28 US disclosed
EP-1497301-B1 SUBSTITUTED POLYCYCLIC, FUSED RING METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2006-11-29 EP disclosed
US-6984602-B2 Olefin polymerization catalysts containing a pyrrole bisimine ligand UNIVATION TECHNOLOGIES, LLC (US) 2006-01-10 US disclosed
US-6946531-B2 Low molecular weight ethylene interpolymers and polymerization process DOW GLOBAL TECHNOLOGIES INC. (US) 2005-09-20 US disclosed
US-6943133-B2 Diene functionalized catalyst supports and supported catalyst compositions UNIVATION TECHNOLOGIES, LLC (US) 2005-09-13 US disclosed
WO-2002074779-A1 METAL COMPLEXES CONTAINING ACETYLENIC LIGANDS, POLYMERIZATION CATALYSTS AND ADDITION POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2002-09-26 WO disclosed
US-20020082161-A1 Diene functionalized catalyst supports and supported catalyst compositions THE DOW CHEMICAL COMPANY 2002-06-27 US disclosed
US-20020072577-A1 Supported catalyst compositions THE DOW CHEMICAL COMPANY 2002-06-13 US disclosed
US-20020062011-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2002-05-23 US disclosed
WO-2002028921-A1 SUPPORTED CATALYST COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2002-04-11 WO disclosed
WO-2002002577-A1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGY INC. (US) 2002-01-10 WO disclosed
US-20010025115-A1 Bridged metal complexes DOW GLOBAL TECHNOLOGIES LLC 2001-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010025115-A1 Bridged metal complexes SLC39A14, NBAS, MCM4 DNM1 967/4885PPARG 3888/4885PPARA 4287/4885
US-20030216529-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process PIN1, ZC3H18, ORC3 DNM1 187/4885PPARG 3228/4885PPARA 2141/4885
US-20020062011-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process PIN1, ZC3H18, ORC3 DNM1 187/4885PPARG 3228/4885PPARA 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.