SCHEMBL3978707

SCHEMBL3978707

CCCN(C#N)c1cc[c]cc1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 3/20 0.35
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CREBBP Q92793 1/20 0.33
POLB P06746 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8041614 0.85
SCHEMBL3448446 0.81 KCNN4 (0.42) DRD3ALDH1A1TSHR
SCHEMBL13158951 0.79 ALDH1A1 (0.41) DRD3ALDH1A1TSHRCREBBPPOLB
SCHEMBL13158982 0.79 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL13158968 0.78 ALDH1A1 (0.40) DRD3ALDH1A1
SCHEMBL128995 0.76 EGFR (0.37) ALDH1A1TSHRPOLBHRH3
SCHEMBL11329200 0.75 CRHR1 (0.39) DRD3ALDH1A1TSHR
SCHEMBL2444957 0.74 MAPT (0.38) POLB
SCHEMBL13158973 0.73 KIF11 (0.39) TSHRHRH3
SCHEMBL4722449 0.72 ALDH1A1 (0.40) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3112864-A1 URINE SAMPLE ANALYSIS METHOD AND REAGENT KIT FOR URINE SAMPLE ANALYSIS Sysmex Corporation (JP) 2017-01-04 EP disclosed
US-20160363588-A1 URINE SAMPLE ANALYSIS METHOD AND REAGENT KIT FOR URINE SAMPLE ANALYSIS SYSMEX CORPORATION (JP) 2016-12-15 US disclosed
US-8309360-B2 Reagent for analyzing urine and method for analyzing urine SYSMEX CORPORATION (JP) 2012-11-13 US disclosed
US-7632683-B2 staining the yeast-like fungi with a fluorescent dye, detecting with light irradiation; detecting urine sample; determining the presence or absence of bleeding in a path from the glomerulus of a kidney to the urethra; analysis; diagnosis SYSMEX CORPORATION (JP) 2009-12-15 US disclosed
EP-1643247-B1 Method, apparatus, reagent kit and reagent for distinguishing erythrocytes in a biological specimen SYSMEX CORP (JP) 2009-06-10 EP disclosed
EP-1837402-B1 Reagent for analyzing urine and method for analyzing urine SYSMEX CORP (JP) 2009-05-13 EP disclosed
US-20070254331-A1 Reagent for analyzing urine and method for analyzing urine SYSMEX CORPORATION (JP) 2007-11-01 US disclosed
EP-1837402-A1 Reagent for analyzing urine and method for analyzing urine Sysmex Corporation (JP) 2007-09-26 EP disclosed
US-20060073601-A1 Method, apparatus, reagent kit and reagent for distinguishing erythrocytes in a biological speciment SYSMEX CORPORATION 2006-04-06 US disclosed
EP-1643247-A1 Method, apparatus, reagent kit and reagent for distingishing erythrocytes in a biological specimen Sysmex Corporation (JP) 2006-04-05 EP disclosed
EP-0708334-B1 Reagent and method for analyzing solid components in urine SYSMEX CORP (JP) 2001-05-23 EP disclosed
EP-1089078-A1 Reagent and method for analyzing solid components in urine Sysmex Corporation (JP) 2001-04-04 EP disclosed
US-5891733-A COMPRISING A BUFFER AGENT, AN OSMOTIC PRESSURE COMPENSATING AGENT,A FIRST DYE WHICH IS A CONDENSED BENZENE DERIVATIVE, A SECOND FLUORESCENT DYE, AND A CHELATING AGENT TOA MEDICAL ELECTRONICS CO., LTD. (JP) 1999-04-06 US disclosed
EP-0708334-A2 Reagent and method for analyzing solid components in urine TOA MEDICAL ELECTRONICS CO., LTD. (JP) 1996-04-24 EP disclosed