Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719828 | 0.92 | EGFR (0.38) | EGFRERBB2CNR2ALDH1A1GFER | |
| SCHEMBL4722449 | 0.91 | ALDH1A1 (0.40) | EGFRERBB2ESRRGCNR2L3MBTL1 | |
| SCHEMBL7035417 | 0.90 | EGFR (0.50) | EGFRERBB2ESRRGCNR2ALDH1A1 | |
| SCHEMBL11329200 | 0.88 | CRHR1 (0.39) | MAPK1ALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL26911777 | 0.87 | HRH3 (0.39) | EGFRERBB2ESRRGCNR2L3MBTL1 | |
| SCHEMBL126299 | 0.86 | EGFR (0.40) | EGFRERBB2CNR2ALDH1A1GFER | |
| SCHEMBL1080080 | 0.85 | EGFR (0.36) | EGFRERBB2CNR2NPC1RAB9A | |
| SCHEMBL9800564 | 0.83 | DNM1 (0.38) | EGFRERBB2CNR2NPC1RAB9A | |
| SCHEMBL9800597 | 0.83 | DNM1 (0.38) | EGFRERBB2CNR2NPC1RAB9A | |
| SCHEMBL2460601 | 0.83 | DNM1 (0.38) | EGFRERBB2CNR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141391-B | Ethylene-polar styrene quasi-random copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-03-13 | — | — | CN | claimed |
| US-20110166132-A1 | Gamma Secretase Modulators | AMGEN INC. (US) | 2011-07-07 | — | — | US | claimed |
| EP-2231602-A1 | GAMMA SECRETASE MODULATORS | Amgen, Inc (US) | 2010-09-29 | — | — | EP | claimed |
| WO-2009075874-A1 | GAMMA SECRETASE MODULATORS | AMGEN INC. (US) | 2009-06-18 | — | — | WO | claimed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | claimed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | claimed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | claimed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |
| US-5492792-A | OPTICAL CARD OR DISKS; EXCELLENT LIGHT SENSITIVITY WITHIN NEAR INFRARED REGION AND HEAT RESISTANCE; STORE INFORMATIONSAT HIGH DENSITY | CANON KABUSHIKI KAISHA (JP) | 1996-02-20 | — | — | US | claimed |
| EP-0402667-B1 | Diarylimidazoles | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-02 | — | — | EP | claimed |
| US-4454211-A | Electrophotographic photosensitive member with pyrazoline charge transport material | CANON KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | claimed |
| US-4420548-A | Electrophotographic member with hydrazone or ketazine compounds | CANON KABUSHIKI KAISHA (JP) | 1983-12-13 | — | — | US | claimed |
| US-4145215-A | PHOTOCONDUCTIVE PIGMENTS | EASTMAN KODAK COMPANY (US) | 1979-03-20 | — | — | US | claimed |
| US-20220404729-A1 | TONER PARTICLES FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE AND TONER COMPOSITION FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE | TOMOEGAWA CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| CN-112513238-A | Stable compositions comprising leuco compounds | 美利肯公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-107141391-B | Ethylene-polar styrene quasi-random copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-03-13 | — | — | CN | disclosed |
| US-4025341-A | CONDENSATION POLYMER OF A TERTIARY AROMATIC AMINE, A SENSITIZER, AND A CARBONYL COMPOUND | EASTMAN KODAK COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-4012376-A | Photosensitive colorant materials | EASTMAN KODAK COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-4008330-A | A P-AMINOPHENYL-THIOUREA | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | EGFR 1813/4885ERBB2 936/4885ESRRG 3303/4885 |
| US-20110166132-A1 | Gamma Secretase Modulators | BACE1, BACE2, PSEN1 | EGFR 3101/4885ERBB2 2732/4885ESRRG 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.