Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16776830 | 0.88 | NQO2 (0.45) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL3971796 | 0.84 | NPSR1 (0.44) | NQO2NPSR1KDM4EPKMRCE1 | |
| SCHEMBL16776811 | 0.84 | NQO2 (0.44) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL16812118 | 0.84 | NQO2 (0.44) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL2345279 | 0.82 | NQO2 (0.47) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL29556356 | 0.82 | NQO2 (0.47) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL14354155 | 0.81 | NPSR1 (0.41) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL1424613 | 0.81 | NQO2 (0.46) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL2342277 | 0.79 | NQO2 (0.45) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL1424864 | 0.79 | NQO2 (0.45) | NQO2NPSR1ABL1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603364-B2 | 4-amino-6-(halo-substituted-alkyl)-picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603364-B2 | 4-amino-6-(halo-substituted-alkyl)-picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603364-B2 | 4-amino-6-(halo-substituted-alkyl)-picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2017-03-28 | — | — | US | disclosed |
| EP-3080083-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015099993-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-07-02 | — | — | WO | disclosed |
| WO-2015099993-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-07-02 | — | — | WO | disclosed |
| US-20150164074-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150164074-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150164074-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-06-18 | — | — | US | disclosed |
| EP-1651607-B1 | 6-(1,1-DIFLUOROALKYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1651607-B1 | 6-(1,1-DIFLUOROALKYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-05-06 | — | — | EP | disclosed |
| US-7291580-B2 | 6-(1,1-difluoroalkyl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291580-B2 | 6-(1,1-difluoroalkyl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291580-B2 | 6-(1,1-difluoroalkyl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2007-11-06 | — | — | US | disclosed |
| EP-1651607-A1 | 6-(1,1-DIFLUOROALKYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005016887-A1 | 6-(1,1-DIFLUOROALKYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050032651-A1 | 6-(1,1-Difluoroalkyl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032651-A1 | 6-(1,1-Difluoroalkyl)-4-aminopicolinates and their use as herbicides | DDT, ALDH7A1, DDC | NQO2 536/4885NPSR1 2907/4885ABL1 303/4885 |
| US-20150164074-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | SLC6A7, HDHD5, DDT | NQO2 1456/4885NPSR1 913/4885ABL1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.