Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343679 | 0.83 | NPSR1 (0.45) | NQO2NPSR1KDM4EPKMRCE1 | |
| SCHEMBL29556356 | 0.83 | NQO2 (0.47) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL2345279 | 0.83 | NQO2 (0.47) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL1424613 | 0.82 | NQO2 (0.46) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL31134746 | 0.82 | NPSR1 (0.44) | NPSR1KDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL2342277 | 0.81 | NQO2 (0.45) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL16029800 | 0.81 | NQO2 (0.45) | NQO2NPSR1ABL1KDM4EPKM | |
| SCHEMBL2344079 | 0.81 | NPSR1 (0.42) | NPSR1ABL1KDM4EPKMRCE1 | |
| SCHEMBL2348206 | 0.80 | TDP1 (0.47) | NQO2KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL3979098 | 0.79 | NQO2 (0.47) | NQO2NPSR1ABL1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731381-B | The polysubstituted aryl of 6-()-4-aminopyridine formic acid esters and the purposes as herbicide thereof | 美国陶氏益农公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| EP-2736897-B1 | SUBSTITUTED PICOLINIC ACIDS AND PYRIMIDINE-4-CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER IP GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| US-9179676-B2 | Substituted picolinic acids and pyrimidine-4-carboxylic acids, method for the production thereof and use thereof as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-10 | — | — | US | disclosed |
| US-9078440-B2 | 6-(2-aminophenyl)picolinates and their use as herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-8962529-B2 | Substituted picolinic acids, salts and acid derivatives thereof, and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20150005165-A1 | SUBSTITUTED PICOLINIC ACIDS AND PYRIMIDINE-4-CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-01 | — | — | US | disclosed |
| EP-2736897-A1 | SUBSTITUTED PICOLINIC ACIDS AND PYRIMIDINE-4-CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer Intellectual Property GmbH (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-20130326735-A1 | 6-(2-Aminophenyl)picolinates and their use as herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-12-05 | — | — | US | disclosed |
| EP-2665710-A1 | 6-(2-AMINOPHENYL)PICOLINATES AND THEIR USE AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-11-27 | — | — | EP | disclosed |
| WO-2004089906-A2 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2004-10-07 | — | — | US | disclosed |
| US-6784137-B2 | SUCH AS 5,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID-N-OXIDE FOR PREEMERGENCE APPLICATION | DOW AGROSCIENCES LLC | 2004-08-31 | — | — | US | disclosed |
| EP-1414814-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2003-06-19 | — | — | US | disclosed |
| WO-2003011853-A1 | 6-ARYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2003-02-13 | — | — | WO | disclosed |
| EP-1246802-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2002-10-09 | — | — | EP | disclosed |
| US-20010047099-A1 | 4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC | 2001-11-29 | — | — | US | disclosed |
| US-6297197-B1 | DEMONSTRATING A BROAD SPECTRUM OF WEED CONTROL. | DOW AGROSCIENCES LLC | 2001-10-02 | — | — | US | disclosed |
| WO-2001051468-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130326735-A1 | 6-(2-Aminophenyl)picolinates and their use as herbicides | HPD, DDT, PTPRG | NQO2 402/4885NPSR1 1479/4885ABL1 2572/4885 |
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | AADAC, AASDHPPT, AADAT | NQO2 1172/4885NPSR1 2922/4885ABL1 572/4885 |
| US-20010047099-A1 | 4-aminopicolinates and their use as herbicides | AADAT, ABAT, DDT | NQO2 1035/4885NPSR1 1632/4885ABL1 561/4885 |
| US-20030114311-A1 | 6-Aryl-4-aminopicolinates and their use as herbicides | AADAC, DDT, AADAT | NQO2 995/4885NPSR1 1629/4885ABL1 375/4885 |
| US-20150005165-A1 | SUBSTITUTED PICOLINIC ACIDS AND PYRIMIDINE-4-CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | HPD, DHFR, PAH | NQO2 139/4885NPSR1 1549/4885ABL1 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.