Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984201 | 0.98 | ALDH1A1 (0.36) | ALDH1A1S1PR1S1PR3TSHRXBP1 | |
| SCHEMBL3990010 | 0.85 | ALDH1A1 (0.39) | ALDH1A1S1PR1S1PR3TSHRXBP1 | |
| SCHEMBL6577776 | 0.79 | ALDH1A1 (0.37) | ALDH1A1S1PR1S1PR3TSHRXBP1 | |
| SCHEMBL28482525 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1SIGMAR1 | |
| SCHEMBL2740855 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1SIGMAR1 | |
| SCHEMBL28482705 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1SIGMAR1 | |
| SCHEMBL3919418 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1SIGMAR1 | |
| SCHEMBL28484902 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1SIGMAR1 | |
| SCHEMBL28484903 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1SIGMAR1 | |
| SCHEMBL28484899 | 0.72 | SIGMAR1 (0.46) | ALDH1A1EPHX1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026754-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137676-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2007-12-06 | — | — | WO | disclosed |