Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 2/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984201 | 0.87 | ALDH1A1 (0.36) | ALDH1A1EPHX1S1PR1S1PR3TSHR | |
| SCHEMBL3980201 | 0.85 | ALDH1A1 (0.33) | ALDH1A1EPHX1S1PR1S1PR3TSHR | |
| SCHEMBL14782937 | 0.74 | MEN1 (0.41) | EPHX1S1PR1S1PR3TSHRXBP1 | |
| SCHEMBL28484903 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1KDM4EMAPTSIGMAR1 | |
| SCHEMBL2740855 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1KDM4EMAPTSIGMAR1 | |
| SCHEMBL4096348 | 0.73 | ALDH1A1 (0.43) | ALDH1A1EPHX1KDM4ES1PR1S1PR3 | |
| SCHEMBL28484902 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1KDM4EMAPTSIGMAR1 | |
| SCHEMBL28482525 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1KDM4EMAPTSIGMAR1 | |
| SCHEMBL3919418 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1KDM4EMAPTSIGMAR1 | |
| SCHEMBL28482705 | 0.73 | SIGMAR1 (0.52) | ALDH1A1EPHX1KDM4EMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026754-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137676-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2007-12-06 | — | — | WO | disclosed |