SCHEMBL398038

SCHEMBL398038

O=C(Cl)c1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.68
MGLL Q99685 13/20 0.62
FAAH O00519 5/20 0.62
NPSR1 Q6W5P4 3/20 0.57
HSP90AA1 P07900 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
PKM P14618 1/20 0.57
MAPK1 P28482 1/20 0.57
ALDH1A1 P00352 3/20 0.54
HPGD P15428 2/20 0.54
HTT P42858 2/20 0.54
CACNA1B Q00975 2/20 0.54
APBA1 Q02410 2/20 0.54
NSD2 O96028 1/20 0.47
G6PD P11413 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
BCHE P06276 1/20 0.47
LMNA P02545 2/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28760459 0.98 DDAH1 (0.66) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL331470 0.83 DDAH1 (0.73) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL235166 0.81 DDAH1 (1.00) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL8463151 0.79 DDAH1 (0.68) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL7923996 0.79 NSD2 (0.62) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL1822680 0.79 DDAH1 (0.96) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL371252 0.79 DDAH1 (0.68) DDAH1MGLLFAAHNPSR1HSP90AA1
Hydrochloric Acid SCHEMBL9278333 0.79 DDAH1 (0.96) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL11320145 0.79 DDAH1 (0.68) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL95324 0.79 MGLL (1.00) DDAH1MGLLFAAHNPSR1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037451-A High-toughness wear-resistant ABS plastic and preparation process thereof 深圳千川健康科技有限公司 2026-05-15 CN claimed
CN-116967463-A Preparation method of silver powder for silver paste on back of solar cell 中科铜都粉体新材料股份有限公司 2023-10-31 CN claimed
CN-101973923-A Naphthalene ring and ester bond structure-containing bismaleimide type compound and preparation method thereof ZHEJIANG UNIVERSITY NINGBO INST OF TECHNOLOGY 2011-02-16 CN claimed
US-4239883-A INFUSIBLE AND INSOLUBLE TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1980-12-16 US claimed
CN-122037451-A High-toughness wear-resistant ABS plastic and preparation process thereof 深圳千川健康科技有限公司 2026-05-15 CN disclosed
US-20240398786-A1 7-ETHYL-10-HYDROXY-CAMPTOTHECIN (SN-38) ALBUMIN CONJUGATES FOR TREATMENT OF CANCERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-12-05 US disclosed
CN-116967463-A Preparation method of silver powder for silver paste on back of solar cell 中科铜都粉体新材料股份有限公司 2023-10-31 CN disclosed
WO-2022088239-A1 MALEIMIDE-MODIFIED ACTIVE ESTER, PREPARATION METHOD THEREFOR AND USE THEREOF 广东生益科技股份有限公司 2022-05-05 WO disclosed
CN-112898561-A Maleimide-terminated polyphenylene ether and preparation method thereof 大连理工大学 2021-06-04 CN disclosed
US-10919241-B2 Self-healing siloxane elastomers BROCK UNIVERSITY (CA) 2021-02-16 US disclosed
US-10919241-B2 Self-healing siloxane elastomers BROCK UNIVERSITY (CA) 2021-02-16 US disclosed
US-20190315934-A1 SELF-HEALING SILOXANE ELASTOMERS BROCK UNIVERSITY (CA) 2019-10-17 US disclosed
EP-0284076-A1 Process for preparing (+)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds SYNTEX (U.S.A.) INC. (US) 1988-09-28 EP disclosed
US-4618492-A Acid-cleavable compound DANA-FARBER CANCER INSTITUTE, INC. (US) 1986-10-21 US disclosed
EP-0191772-A1 ACID-CLEAVABLE COMPOUND. DANA FARBER CANCER INST INC (US) 1986-08-27 EP disclosed
WO-1986001409-A1 ACID-CLEAVABLE COMPOUND DANA-FARBER CANCER INSTITUTE, INC. (US) 1986-03-13 WO disclosed
US-4569789-A Acid-cleavable compound, use in protein conjugates and drug delivery systems DANA-FARBER CANCER INSTITUTE, INC. (US) 1986-02-11 US disclosed
US-4542225-A CROSSLINKING AGENTS DANA-FARBER CANCER INSTITUTE, INC. (US) 1985-09-17 US disclosed
US-4269966-A A MIXTURE OF AN ACRYLIC COMPOUND CONTAINING IMIDE, AMIDE, AND AN AMINE GROUP; MOLDING MATERIAL; CROSSLINKED, INSOLUBLE, INFUSIBLE POLYMER TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1981-05-26 US disclosed
US-4239883-A INFUSIBLE AND INSOLUBLE TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1980-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398786-A1 7-ETHYL-10-HYDROXY-CAMPTOTHECIN (SN-38) ALBUMIN CONJUGATES FOR TREATMENT OF CANCERS ALB, RPL38, TP53 DDAH1 2305/4885MGLL 2773/4885FAAH 2555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.