SCHEMBL8463151

SCHEMBL8463151

NC(=O)c1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.68
MGLL Q99685 13/20 0.62
FAAH O00519 5/20 0.62
NPSR1 Q6W5P4 3/20 0.57
HSP90AA1 P07900 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
PKM P14618 1/20 0.57
MAPK1 P28482 1/20 0.57
ALDH1A1 P00352 3/20 0.54
HPGD P15428 2/20 0.54
HTT P42858 2/20 0.54
LMNA P02545 2/20 0.54
CACNA1B Q00975 2/20 0.54
APBA1 Q02410 2/20 0.54
MAPT P10636 1/20 0.54
NSD2 O96028 1/20 0.47
G6PD P11413 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26066669 0.87 DDAH1 (0.53) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL331470 0.83 DDAH1 (0.73) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL235166 0.81 DDAH1 (1.00) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL371252 0.79 DDAH1 (0.68) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL1822680 0.79 DDAH1 (0.96) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL11320145 0.79 DDAH1 (0.68) DDAH1MGLLFAAHNPSR1HSP90AA1
Hydrochloric Acid SCHEMBL9278333 0.79 DDAH1 (0.96) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL398038 0.79 DDAH1 (0.68) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL95324 0.79 MGLL (1.00) DDAH1MGLLFAAHNPSR1HSP90AA1
SCHEMBL10515423 0.79 PARP1 (0.65) MGLLFAAHNPSR1HSP90AA1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901751-A Thermosetting resin composition, prepreg, laminate, printed wiring board, and semiconductor package 昭和电工材料株式会社 2022-08-12 CN disclosed
WO-2017177316-A1 AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS 3R VALO, S.E.C. (CA) 2017-10-19 WO disclosed
US-20170000897-A1 MONOMETHYLVALINE COMPOUNDS CAPABLE OF CONJUGATION TO LIGANDS SEATTLE GENETICS, INC. 2017-01-05 US disclosed
CN-104981693-A Method for producing labeled antibody FURUKAWA ELECTRIC CO LTD 2015-10-14 CN disclosed
CN-103339536-B Pyrrolopyrrole dione pigment composition for color filter, coloring composition for color filter, and color filter TOYO INK SC HOLDINGS CO LTD 2015-07-22 CN disclosed
CN-103370642-B Colored composition for color filters, and color filter TOYO INK SC HOLDINGS CO LTD 2015-07-15 CN disclosed
CN-104736516-A High-purity sodium p-styrenesulfonate having excellent hue, process for producing the same, sodium polystyrenesulfonate having excellent hue using the same, dispersant using the sodium polystyrenesulfonate, and synthetic paste for finishing clothing TOSOH ORGANIC CHEMICAL CO LTD 2015-06-24 CN disclosed
US-8703714-B2 Monomethylvaline compounds capable of conjugation to ligands SEATTLE GENETICS, INC. (US) 2014-04-22 US disclosed
CN-103370642-A Colored composition for color filters, and color filter TOYO INK SC HOLDINGS CO LTD 2013-10-23 CN disclosed
US-8557780-B2 Monomethylvaline compounds capable of conjugation to ligands SEATTLE GENETICS, INC. (US) 2013-10-15 US disclosed
EP-0190507-B1 FLAME RETARDANT MOLDED COMPOSITION WHICH INCORPORATES A POLY (N-(BROMOPHENYL) MALEIMIDE-CO-STYRENE-CO-N-PHENYLMALEIMIDE)) COPOLYMER ARCO CHEMICAL TECHNOLOGY, INC. (US) 1989-05-10 EP disclosed
US-4684692-A Flame-retardant molded composition which incorporates a poly(styrene-CO-N-phenylmaleimide-CO-dibromostyrene) copolymer ATLANTIC RICHFIELD COMPANY (US) 1987-08-04 US disclosed
US-4668750-A Flame-retardant molded composition which incorporates a poly(styrene-co-N-phenylmaleimide-co-dibromostyrene) copolymer ATLANTIC RICHFIELD COMPANY (US) 1987-05-26 US disclosed
US-4663386-A Flame-retardant molded composition which incorporates a poly(styrene-co-N-phenylmaleimide-co-dibromostyrene)copolymer ATLANTIC RICHFIELD COMPANY (US) 1987-05-05 US disclosed
US-4661574-A SYNERGISTIC ATLANTIC RICHFIELD COMPANY (US) 1987-04-28 US disclosed
US-4625004-A Flame-retardant molded composition which incorporates a poly (styrene-CO-N-phenylmaleimide-CO-dibromostyrene copolymer ATLANTIC RICHFIELD COMPANY (US) 1986-11-25 US disclosed
US-4609711-A AND SYNERGIST ATLANTIC RICHFIELD COMPANY (US) 1986-09-02 US disclosed
EP-0190507-A1 Flame retardant molded composition which incorporates a poly (N-(bromophenyl) maleimide-co-styrene-co-N-phenylmaleimide)) copolymer ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-08-13 EP disclosed
EP-0188905-A1 Flame retardant molded composition which incorporates a poly (styrene-co-N-phenylmaleimide-co-dibromostyrene) ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-07-30 EP disclosed
US-4528020-A Urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1985-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170000897-A1 MONOMETHYLVALINE COMPOUNDS CAPABLE OF CONJUGATION TO LIGANDS MMAB, CAD, VIM DDAH1 318/4885MGLL 4454/4885FAAH 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.