SCHEMBL3980884

SCHEMBL3980884

[CH2]CCCCCCC#CCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN7 P35236 5/20 0.50
▸ HMGCR P04035 3/20 0.50
▸ RECQL P46063 2/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ TSHR P16473 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ USP2 O75604 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ EPHX2 P34913 3/20 0.39
▸ RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7997923 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3868090 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL9320884 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL17287304 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3989821 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL17608718 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3840581 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3856545 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3859291 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL9209758 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117128-A1 INTRAOCULAR PRESSURE LOWERING AGENT, AND AGENT FOR TREATING OR PREVENTING GLAUCOMA OR OCULAR HYPERTENSION SANSHO株式会社 2024-06-06 — — WO disclosed
US-20240115586-A1 THERAPEUTIC AGENT FOR PULMONARY FIBROSIS SANSHO CO. LTD. (JP) 2024-04-11 — — US disclosed
EP-4252756-A1 THERAPEUTIC AGENT FOR PULMONARY FIBROSIS Sansho Co., Ltd. (JP) 2023-10-04 — — EP disclosed
CN-116710105-A Therapeutic agent for pulmonary fibrosis 山椒株式会社 2023-09-05 — — CN disclosed
US-20230108750-A1 CARBALYSOPHOSPHATIDIC ACID OCHANOMIZU UNIVERSITY (JP) 2023-04-06 — — US disclosed
US-10562919-B2 Complex and process for preparing complex SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2020-02-18 — — US disclosed
US-10413559-B2 Method for treating demyelinating disease OCHANOMIZU UNIVERSITY (JP) 2019-09-17 — — US disclosed
US-10322317-B2 Rubber composition, crosslinked rubber molded product and golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-06-18 — — US disclosed
US-10293215-B2 Rubber composition, crosslinked rubber molded product and golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-21 — — US disclosed
EP-2949329-B1 THERAPEUTIC AGENT FOR DEMYELINATING DISEASE UNIV OCHANOMIZU (JP) 2019-05-01 — — EP disclosed
EP-1402894-A1 CANCEROUS METASTASIS INHIBITORS CONTAINING CARBACYCLIC PHOSPHATIDIC ACID DERIVATIVES Gencom Corporation (JP) 2004-03-31 — — EP disclosed
EP-1391204-A1 NERVE CELL SURVIVAL PROMOTERS CONTAINING CYCLIC PHOSPHATIDIC ACID DERIVATIVE Gencom Corporation (JP) 2004-02-25 — — EP disclosed
EP-1386612-A1 DRUGS FO RPROMOTING THE PROLIFERATION, DIFFERENTIATION AND/OR SURVIVAL OF GLIAL CELLS CONTAINING CYCLIC PHOSPHATIDIC ACID Gencom Corporation (JP) 2004-02-04 — — EP disclosed
US-6284784-B1 2-HYDROXYMETHYL DERIVATIVES GEORGETOWN UNIVERSITY 2001-09-04 — — US disclosed
EP-1015427-A1 SUBSTITUTED 2-PYRROLIDINONE ACTIVATORS OF PKC GEORGETOWN UNIVERSITY (US) 2000-07-05 — — EP disclosed
US-5962504-A ACTIVATOR OF PROTEIN KINASE; ANTICANCER AGENT GEORGETOWN UNIVERSITY (US) 1999-10-05 — — US disclosed
WO-1999012901-A1 SUBSTITUTED 2-PYRROLIDINONE ACTIVATORS OF PKC GEORGETOWN UNIVERSITY (US) 1999-03-18 — — WO disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 — — EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 — — US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230108750-A1 CARBALYSOPHOSPHATIDIC ACID PHOSPHO1, SGMS1, PLD1 PTPN7 2293/4885HMGCR 1411/4885RECQL 3592/4885
US-10293215-B2 Rubber composition, crosslinked rubber molded product and golf ball GIGYF2, RACK1, COG1 PTPN7 3192/4885HMGCR 3479/4885RECQL 2554/4885
US-10413559-B2 Method for treating demyelinating disease PMP22, MAG, SGMS1 PTPN7 1364/4885HMGCR 685/4885RECQL 2785/4885
US-20240115586-A1 THERAPEUTIC AGENT FOR PULMONARY FIBROSIS CCL11, ELANE, MMP1 PTPN7 3368/4885HMGCR 1408/4885RECQL 4011/4885
US-10562919-B2 Complex and process for preparing complex SCO2, AP1M1, AP3M1 PTPN7 4347/4885HMGCR 3268/4885RECQL 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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