Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975696 | 0.88 | PRKCZ (0.45) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL4932598 | 0.87 | HSD17B10 (0.51) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3980970 | 0.85 | ALDH1A1 (0.65) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3981694 | 0.85 | PRKCZ (0.62) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3975112 | 0.84 | PRKCZ (0.50) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3976253 | 0.84 | PRKCZ (0.50) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3975901 | 0.81 | ALDH1A1 (0.73) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3980569 | 0.81 | ADORA1 (0.61) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL3979142 | 0.80 | ALDH1A1 (0.65) | ALDH1A1PRKCZLMNAHPGDMEN1 | |
| SCHEMBL27653910 | 0.77 | PBRM1 (0.51) | ALDH1A1PRKCZLMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |