Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982080 | 0.82 | FDPS (0.69) | FDPSHDAC6P2RX7GGPS1P2RY1 | |
| SCHEMBL27921679 | 0.81 | CYP3A4 (0.75) | FDPSCYP3A4 | |
| SCHEMBL3981358 | 0.80 | FDPS (0.67) | FDPSHDAC6P2RX7CYP3A4FGFR1 | |
| SCHEMBL23323404 | 0.78 | FDPS (0.63) | FDPSHDAC6P2RX7FGFR1FGFR4 | |
| SCHEMBL11252936 | 0.78 | ADORA2A (0.68) | FDPSHDAC6P2RX7CYP3A4FGFR1 | |
| SCHEMBL3977299 | 0.77 | FDPS (0.63) | FDPSHDAC6P2RX7CYP3A4GGPS1 | |
| SCHEMBL9563452 | 0.76 | FDPS (0.61) | FDPSHDAC6P2RX7CYP3A4FGFR1 | |
| SCHEMBL11597681 | 0.76 | FDPS (0.61) | FDPSHDAC6P2RX7FGFR1FGFR4 | |
| SCHEMBL11596728 | 0.76 | FDPS (0.61) | FDPSHDAC6P2RX7FGFR1FGFR4 | |
| SCHEMBL11597828 | 0.75 | FDPS (0.60) | FDPSHDAC6P2RX7FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | claimed |
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | disclosed |