Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.69 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983260 | 0.82 | FDPS (1.00) | FDPSP2RY1P2RX7GGPS1HDAC6 | |
| SCHEMBL183219 | 0.78 | HDAC1 (0.50) | FDPSP2RY1P2RX7HDAC4HDAC1 | |
| SCHEMBL3348188 | 0.78 | P2RX7 (0.48) | FDPSP2RY1P2RX7HDAC4HDAC1 | |
| SCHEMBL3984337 | 0.78 | FDPS (0.51) | FDPSP2RY1P2RX7GGPS1 | |
| SCHEMBL5161430 | 0.75 | P2RX7 (0.46) | FDPSP2RY1P2RX7HDAC1 | |
| SCHEMBL3980736 | 0.75 | FDPS (0.54) | FDPSP2RY1GGPS1 | |
| SCHEMBL11961126 | 0.73 | P2RX7 (0.52) | P2RY1P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL12537292 | 0.73 | P2RX7 (0.47) | FDPSP2RY1P2RX7HDAC4HDAC1 | |
| SCHEMBL29444616 | 0.72 | CDK1 (0.51) | P2RX7HDAC4HDAC1HDAC6 | |
| SCHEMBL183244 | 0.72 | CDK1 (0.51) | P2RX7HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | claimed |