Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.63 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984337 | 0.82 | FDPS (0.51) | FDPSGGPS1P2RY1P2RX7 | |
| SCHEMBL3983260 | 0.77 | FDPS (1.00) | FDPSGGPS1HDAC6CYP3A4P2RY1 | |
| SCHEMBL3983479 | 0.73 | FDPS (0.39) | FDPSADORA2A | |
| SCHEMBL4262821 | 0.72 | FDPS (0.62) | FDPSGGPS1HDAC6CYP3A4HDAC1 | |
| SCHEMBL2063606 | 0.72 | ADORA2A (0.64) | FDPSADORA2AP2RX7 | |
| SCHEMBL3979481 | 0.70 | FDPS (0.49) | FDPSGGPS1CYP3A4P2RY1 | |
| SCHEMBL7977956 | 0.68 | KDM4E (0.49) | FDPSADORA2AP2RY1P2RX7 | |
| SCHEMBL3982080 | 0.68 | FDPS (0.69) | FDPSGGPS1HDAC6P2RY1P2RX7 | |
| SCHEMBL3476218 | 0.67 | ADORA2A (0.47) | ADORA2A | |
| SCHEMBL3986005 | 0.67 | FDPS (0.51) | FDPSGGPS1CYP3A4P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | claimed |
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | disclosed |