Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 3/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983824 | 0.82 | LMNA (0.38) | ALOX15MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL3989062 | 0.80 | PTGDR2 (0.49) | MAPTTSHRTDP1 | |
| SCHEMBL3981440 | 0.78 | MEN1 (0.38) | ERCC1ERCC4ALOX15PTGESMAPT | |
| SCHEMBL3985878 | 0.77 | PTGDR (0.51) | PTGESMAPTKMT2ACNR1KDM4E | |
| SCHEMBL3989921 | 0.69 | LMNA (0.41) | ALOX15MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL12611071 | 0.62 | HSD17B10 (0.48) | ALOX15MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL3984323 | 0.61 | LMNA (0.43) | ALOX15MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4395732 | 0.60 | MAPT (0.49) | ALOX15MAPTMEN1KMT2ACASP1 | |
| SCHEMBL3983803 | 0.60 | HTR2C (0.41) | ERCC1ERCC4ALOX15IGF1RMAPT | |
| SCHEMBL24715777 | 0.59 | KDM4E (0.44) | ALOX15MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |