Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984323 | 0.82 | LMNA (0.43) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL3985312 | 0.79 | TDP1 (0.47) | MAPTHPGDHSD17B10 | |
| SCHEMBL3989567 | 0.78 | LMNA (0.41) | KMT2AMAPTHPGDHIF1APARP1 | |
| SCHEMBL3984015 | 0.78 | ERCC1 (0.37) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL3989921 | 0.73 | LMNA (0.41) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL3771921 | 0.68 | CCNE2 (0.39) | KMT2ACCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL31301800 | 0.66 | KDM4E (0.47) | MAPTALOX15PARP1 | |
| SCHEMBL4187887 | 0.66 | SELPLG (0.48) | CYP3A4FABP4LDHALDHB | |
| SCHEMBL3984739 | 0.65 | LMNA (0.38) | MEN1KMT2AMAPTCYP3A4HPGD | |
| SCHEMBL10826427 | 0.64 | CYP3A4 (0.47) | MEN1KMT2AMAPTCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |