Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985878 | 0.89 | PTGDR (0.51) | PTGDR2PTGDRPTGER2TDP1TSHR | |
| SCHEMBL3983824 | 0.83 | LMNA (0.38) | TSHRMAPT | |
| SCHEMBL3985312 | 0.82 | TDP1 (0.47) | PTGDR2PTGDRTDP1TSHRPPARD | |
| SCHEMBL3984015 | 0.80 | ERCC1 (0.37) | TDP1TSHRMAPT | |
| SCHEMBL3988279 | 0.76 | TDP1 (0.47) | PTGDR2PTGDRTDP1TSHRPPARD | |
| SCHEMBL3989567 | 0.73 | LMNA (0.41) | PTGDR2PTGDRTDP1TSHRMAPT | |
| SCHEMBL3983777 | 0.71 | TDP1 (0.55) | PTGDR2PTGDRPTGER2TDP1TSHR | |
| SCHEMBL10732488 | 0.69 | PTGDR2 (0.70) | PTGDR2PTGDRPTGER2TDP1TSHR | |
| SCHEMBL3771025 | 0.69 | TDP1 (0.48) | PTGDR2PTGDRTDP1TSHRPPARD | |
| SCHEMBL3983651 | 0.68 | PTGDR2 (0.43) | PTGDR2TDP1TSHRPPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |