SCHEMBL3984069

SCHEMBL3984069

CC1CCC2C(C1)C2OC(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3984150 0.76 MAPT (0.33) EPHX1CYP19A1
SCHEMBL3983190 0.73 MEN1 (0.33)
SCHEMBL3979936 0.73 POLB (0.32) EPHX1
SCHEMBL13195790 0.72 CYP19A1 (0.46) EPHX1CYP19A1
SCHEMBL3983989 0.72 CES2 (0.36) EPHX1
SCHEMBL2489754 0.71 EPHX1 (0.37) EPHX1CYP19A1
SCHEMBL3981115 0.71 PTPN1 (0.31)
SCHEMBL3984067 0.68 POLB (0.37) EPHX1
SCHEMBL34468414 0.68 POLB (0.37) EPHX1
SCHEMBL5076651 0.68 POLB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1562575-B1 FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY ABBOTT LAB (US) 2009-05-20 EP claimed