Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | LIPA | P38571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984069 | 0.76 | EPHX1 (0.31) | EPHX1CYP19A1 | |
| SCHEMBL3984148 | 0.72 | EPHX1 (0.34) | EPHX1KDM4EHTTGLALIPA | |
| SCHEMBL28199763 | 0.71 | MAPT (0.51) | MAPTAPOBEC3AAPOBEC3GEPHX1KDM4E | |
| SCHEMBL27052182 | 0.70 | MAPT (0.45) | MAPTAPOBEC3AAPOBEC3GGLAGAA | |
| SCHEMBL3979936 | 0.69 | POLB (0.32) | EPHX1KDM4E | |
| SCHEMBL3983190 | 0.69 | MEN1 (0.33) | — | |
| SCHEMBL3983989 | 0.68 | CES2 (0.36) | MAPTEPHX1KDM4ESMN1; SMN2 | |
| SCHEMBL3981105 | 0.67 | EPHX1 (0.33) | MAPTEPHX1LIPA | |
| SCHEMBL3984368 | 0.66 | LMNA (0.33) | SMN1; SMN2 | |
| SCHEMBL4975666 | 0.65 | LMNA (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562575-B1 | FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY | ABBOTT LAB (US) | 2009-05-20 | — | — | EP | claimed |