Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 4/20 | 0.44 |
| ▸ | CMA1 | P23946 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392165 | 0.84 | ALDH1A1 (0.49) | ALDH1A1USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL9834330 | 0.84 | KMT2A (0.61) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL1750928 | 0.79 | NPC1 (0.52) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL28844401 | 0.79 | NPC1 (0.56) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL6363201 | 0.77 | NPC1 (0.67) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL6362412 | 0.76 | HPGD (0.53) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL11879033 | 0.75 | KMT2A (0.42) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL2550882 | 0.74 | RAB9A (0.41) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL5309857 | 0.73 | MAPT (0.47) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL14541451 | 0.72 | NPC1 (0.48) | KMT2ANPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349888-B | Novel alkynyl-substituted 3-phenylpyrrolidine-2, 4-diones and their use as herbicides | 拜耳作物科学股份公司 | 2022-03-25 | — | — | CN | claimed |
| US-11178868-B2 | Alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-11-23 | — | — | US | claimed |
| CN-107922333-B | Novel alkynyl-substituted 3-phenylpyrrolidine-2, 4-diones and their use as herbicides | 拜耳作物科学股份公司 | 2021-03-30 | — | — | CN | claimed |
| US-10899709-B2 | Novel-alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-01-26 | — | — | US | claimed |
| EP-3359525-B1 | NEW ALKYNYL-SUBSTITUTED 3-PHENYLPYRROLIDIN-2,4-DIONES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2021-01-06 | — | — | EP | claimed |
| US-20190174758-A1 | New alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-06-13 | — | — | US | claimed |
| EP-3310759-B1 | NEW ALKYNYLSUBSTITUTED 3-PHENYLPYRROLIDIN-2,4-DIONE AND THEIR USE AS HERBICIDE | BAYER CROPSCIENCE AG (DE) | 2019-03-20 | — | — | EP | claimed |
| US-20180170872-A1 | NOVEL-ALKYNYL-SUBSTITUTED 3-PHENYLPYRROLIDINE-2,4-DIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-21 | — | — | US | claimed |
| CN-108349888-B | Novel alkynyl-substituted 3-phenylpyrrolidine-2, 4-diones and their use as herbicides | 拜耳作物科学股份公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-108349888-B | Novel alkynyl-substituted 3-phenylpyrrolidine-2, 4-diones and their use as herbicides | 拜耳作物科学股份公司 | 2022-03-25 | — | — | CN | disclosed |
| US-20210400966-A1 | NEW ALKYNYL-SUBSTITUTED 3-PHENYLPYRROLIDINE-2,4-DIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-12-30 | — | — | US | disclosed |
| US-20210400966-A1 | NEW ALKYNYL-SUBSTITUTED 3-PHENYLPYRROLIDINE-2,4-DIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-12-30 | — | — | US | disclosed |
| US-11178868-B2 | Alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-11-23 | — | — | US | disclosed |
| US-11178868-B2 | Alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-11-23 | — | — | US | disclosed |
| EP-0415211-A2 | 3-Aryl-pyrrolidin-2,4-dione derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4257957-A | Methyl-tris-(4-hydroxycoumarin)silane | GENERAL ELECTRIC COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4238401-A | ALKANOL, HALOSILANE, 1,3-DICARBONYL CYCLIC COMPOUND, VULCANIZATION AGENTS | GENERAL ELECTRIC COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| US-4210596-A | Silyl ethers of 1,3-dicarbonyl cyclic compounds | GENERAL ELECTRIC COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190174758-A1 | New alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | HDHD5, DDT, HPD | KMT2A 1245/4885NPC1 4554/4885RAB9A 2851/4885 |
| US-20210400966-A1 | NEW ALKYNYL-SUBSTITUTED 3-PHENYLPYRROLIDINE-2,4-DIONES AND USE THEREOF AS HERBICIDES | HDHD5, DDT, HPD | KMT2A 1245/4885NPC1 4554/4885RAB9A 2851/4885 |
| US-20180170872-A1 | NOVEL-ALKYNYL-SUBSTITUTED 3-PHENYLPYRROLIDINE-2,4-DIONES AND USE THEREOF AS HERBICIDES | CBR3, HDHD5, DDT | KMT2A 1423/4885NPC1 4512/4885RAB9A 3695/4885 |
| US-10899709-B2 | Novel-alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | CBR3, HDHD5, DDT | KMT2A 1423/4885NPC1 4512/4885RAB9A 3695/4885 |
| US-11178868-B2 | Alkynyl-substituted 3-phenylpyrrolidine-2,4-diones and use thereof as herbicides | HDHD5, HPD, CBR3 | KMT2A 1590/4885NPC1 4489/4885RAB9A 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.