Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31085369 | 0.87 | MAPT (0.35) | GAAMAPTPKMTSHRALDH1A1 | |
| SCHEMBL3469591 | 0.81 | MAPT (0.49) | GAAMAPTPKMKDM4ETSHR | |
| SCHEMBL3986231 | 0.72 | MAPT (0.47) | GAAMAPTPKMKDM4ETSHR | |
| SCHEMBL30518402 | 0.69 | PKM (0.40) | MAPTPKM | |
| SCHEMBL7801786 | 0.68 | ALDH1A1 (0.45) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8663859 | 0.67 | MAPT (0.47) | GAAMAPTKDM4ETSHRALDH1A1 | |
| SCHEMBL8803147 | 0.66 | MAPT (0.46) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9761816 | 0.66 | GAA (0.45) | GAAMAPTKDM4EALDH1A1ADORA3 | |
| SCHEMBL8594839 | 0.65 | ALDH1A1 (0.46) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5698112 | 0.65 | TSHR (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058387-A2 | OLIGOMER-NITROIMIDAZOLE ANTI-INFECTIVE CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-05-07 | — | — | WO | claimed |