SCHEMBL398496

SCHEMBL398496

C=C(Cc1cccc(S(=O)(=O)NC)c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
EGFR P00533 2/20 0.43
ERBB2 P04626 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.40
PTBP1 P26599 1/20 0.40
IDH1 O75874 1/20 0.40
AKR1C3 P42330 2/20 0.40
GRK6 P43250 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TNNI3K Q59H18 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HTT P42858 1/20 0.39
FBP1 P09467 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL392888 0.86 ALDH1A1 (0.45) EGFRERBB2LMNAAKR1C3HDAC2
SCHEMBL3846633 0.85 PTGDR2 (0.49) POLBEGFRERBB2TDP1LMNA
SCHEMBL398535 0.85 KDM4E (0.52) EGFRERBB2LMNAAKR1C3SMN1; SMN2
SCHEMBL397724 0.84 AKR1C3 (0.48) AKR1C3HDAC2HDAC8HDAC6HTT
SCHEMBL396990 0.83 HTR6 (0.59) POLBHDAC2HDAC8HDAC6
SCHEMBL28183347 0.82 NQO2 (0.45) POLBEGFRERBB2TDP1LMNA
SCHEMBL395695 0.82 SMN1; SMN2 (0.46) EGFRERBB2LMNASMN1; SMN2HTT
SCHEMBL395829 0.82 ALDH1A1 (0.45) POLBLMNAL3MBTL1SMN1; SMN2HTT
SCHEMBL397008 0.82 ALDH1A1 (0.49) LMNAAKR1C3SMN1; SMN2HDAC2HDAC8
SCHEMBL397249 0.81 CA1 (0.48) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed