Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PARG | Q86W56 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398496 | 0.85 | POLB (0.44) | LMNASMN1; SMN2EGFRERBB2HDAC2 | |
| SCHEMBL398265 | 0.83 | ALDH1A1 (0.49) | LMNAMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30415039 | 0.83 | LMNA (0.58) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL392888 | 0.83 | ALDH1A1 (0.45) | LMNAKMT2AEGFRERBB2HDAC2 | |
| SCHEMBL7266380 | 0.82 | LMNA (0.52) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL397008 | 0.81 | ALDH1A1 (0.49) | KDM4ELMNAKMT2ASMN1; SMN2HDAC2 | |
| SCHEMBL397724 | 0.81 | AKR1C3 (0.48) | KMT2AHDAC2HDAC8HDAC6HTT | |
| SCHEMBL396990 | 0.80 | HTR6 (0.59) | MEN1KMT2AHDAC2HDAC8HDAC6 | |
| SCHEMBL2854642 | 0.79 | MAPT (0.63) | KDM4EMEN1NPC1LMNAMAPT | |
| SCHEMBL395829 | 0.79 | ALDH1A1 (0.45) | LMNAMAPTSMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |