Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396887 | 0.92 | HTR6 (0.62) | HTR6HDAC8HDAC2HDAC6POLB | |
| SCHEMBL393833 | 0.88 | AKR1C3 (0.61) | HTR6HDAC8HDAC2HDAC6PGR | |
| SCHEMBL396993 | 0.85 | ALDH1A1 (0.58) | HTR6HDAC8HDAC2HDAC6MEN1 | |
| SCHEMBL397676 | 0.85 | HDAC1 (0.68) | HTR6HDAC8POLBIL1RNKEAP1 | |
| SCHEMBL396740 | 0.85 | HDAC1 (0.59) | HTR6HDAC8IL1RNKEAP1ERAP1 | |
| SCHEMBL28182427 | 0.83 | HTR6 (0.62) | HTR6HDAC8HDAC2HDAC6PGR | |
| SCHEMBL398496 | 0.83 | POLB (0.44) | HDAC8HDAC2HDAC6POLB | |
| SCHEMBL392908 | 0.83 | KMT2A (0.61) | MEN1KMT2AALDH1A1 | |
| SCHEMBL392888 | 0.81 | ALDH1A1 (0.45) | HDAC8HDAC2HDAC6KMT2AALDH1A1 | |
| SCHEMBL398535 | 0.80 | KDM4E (0.52) | HDAC8HDAC2HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |