Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.56 |
| ▸ | HTR3A | P46098 | 13/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAT2A | P31153 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003486 | 0.87 | ELANE (0.50) | ELANEHTR3AKCNH2HSD17B10 | |
| SCHEMBL1003484 | 0.87 | ELANE (0.50) | ELANEHTR3AKCNH2HSD17B10 | |
| SCHEMBL3984732 | 0.80 | ELANE (0.52) | ELANEMAT2AHSD17B10 | |
| SCHEMBL12928116 | 0.79 | HTR3A (0.71) | HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL1005617 | 0.79 | HTR3A (0.70) | HTR3AKCNH2 | |
| SCHEMBL7846334 | 0.76 | ELANE (0.67) | ELANEHTR3A | |
| SCHEMBL1004884 | 0.75 | HTR6 (0.50) | ELANEHTR3AKCNH2IDO1MAOA | |
| SCHEMBL8223628 | 0.75 | HTR3A (0.47) | ELANEHTR3AKCNH2 | |
| SCHEMBL5108964 | 0.73 | HTR3A (0.65) | HTR3AKCNH2 | |
| SCHEMBL3984980 | 0.73 | HTR3A (0.65) | HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061460-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | Albany Molecular Research, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008019372-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2008-02-14 | — | — | WO | disclosed |