SCHEMBL3986446

SCHEMBL3986446

COc1c(C=CC(=O)OO[Si](C)(C)C)c([SiH3])c(CCC(C)C)c(OC)c1OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19177415 1.00 LMNA (0.33) LMNATDP1
SCHEMBL942222 0.70 KDM4E (0.36)
SCHEMBL22500107 0.60 ABCG2 (0.59) LMNA
SCHEMBL22500105 0.60 ABCG2 (0.59) LMNA
SCHEMBL22070142 0.59 ALOX5 (0.37) LMNATDP1
SCHEMBL21625542 0.59 ALOX5 (0.39) LMNATDP1
SCHEMBL29046241 0.57 KDM4E (0.36)
SCHEMBL28238937 0.56 CA1 (0.45) TDP1
SCHEMBL27455747 0.55 LMNA (0.52) LMNATDP1
SCHEMBL4448331 0.55 GLA (0.52) LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352638-B1 COSMETICS FOR ALLEVIATING SKIN IRRITATION SHISEIDO CO LTD (JP) 2009-05-20 EP disclosed
US-7169379-B2 Cosmetics SHISEIDO CO., LTD. (JP) 2007-01-30 US disclosed
EP-1352638-A1 COSMETICS SHISEIDO COMPANY, LTD. (JP) 2003-10-15 EP disclosed
US-20030185772-A1 Cosmetics SHISEIDO COMPANY, LTD. (JP) 2003-10-02 US disclosed