Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986446 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL19177415 | 0.70 | LMNA (0.33) | — | |
| SCHEMBL2290699 | 0.69 | KDM4E (0.51) | KDM4EHTTALDH1A1HTR1AHPGD | |
| SCHEMBL646616 | 0.67 | KDM4E (0.43) | KDM4EHTTALDH1A1HTR1AHPGD | |
| SCHEMBL646614 | 0.67 | KDM4E (0.43) | KDM4EHTTALDH1A1HTR1AHPGD | |
| SCHEMBL23706404 | 0.66 | ALDH1A1 (0.42) | KDM4EHTTALDH1A1HTR1AHPGD | |
| SCHEMBL23706403 | 0.66 | ALDH1A1 (0.42) | KDM4EHTTALDH1A1HTR1AHPGD | |
| SCHEMBL28238937 | 0.66 | CA1 (0.45) | KDM4EHTTSMPD1ALDH1A1HTR1A | |
| SCHEMBL2290706 | 0.64 | ALOX5 (0.43) | KDM4EHTTALDH1A1HTR1AHPGD | |
| SCHEMBL29046241 | 0.64 | KDM4E (0.36) | KDM4EHTTALDH1A1HTR1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10406135-B2 | Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group | CLARIANT INTERNATIONAL LTD. (CH) | 2019-09-10 | — | — | US | disclosed |
| US-9526687-B2 | Polymers based on sulfonic acids, amides and special cross-linking agents | CLARIANT INTERNATIONAL LTD. (CH) | 2016-12-27 | — | — | US | disclosed |
| US-9295626-B2 | Compositions comprising isosorbide monoester and N-hydroxypyridones | CLARIANT INTERNATIONAL LTD. (CH) | 2016-03-29 | — | — | US | disclosed |
| US-20160000080-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALIPHATIC VICINAL DIOLS | CLARIANT INTERNATIONAL LTD. (CH) | 2016-01-07 | — | — | US | disclosed |
| US-20150342856-A1 | Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-12-03 | — | — | US | disclosed |
| US-20140369943-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE COMPOUNDS | CLARIANT INTERNATIONAL LTD. (CH) | 2014-12-18 | — | — | US | disclosed |
| US-20140348763-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-27 | — | — | US | disclosed |
| US-20140343171-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTER AND N-HYDROXYPYRIDONES | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140329870-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-06 | — | — | US | disclosed |
| US-20140308224-A1 | COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS COMPRISING ISOSORBIDE DIESTERS AND UV FILTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2014-10-16 | — | — | US | disclosed |
| US-20100278760-A1 | Cosmetics | SHISEIDO COMPANY,LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-20100260696-A1 | Aqueous Compositions Containing Alkoxylated Phosphoric Acid Triesters | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-10-14 | — | — | US | disclosed |
| WO-2009149879-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITIONS COMPRISING MODIFIED POLYSILOXANES WITH AT LEAST ONE CARBAMATE GROUP | CLARIANT INTERNATIONAL LTD (CH) | 2009-12-17 | — | — | WO | disclosed |
| EP-1352638-B1 | COSMETICS FOR ALLEVIATING SKIN IRRITATION | SHISEIDO CO LTD (JP) | 2009-05-20 | — | — | EP | disclosed |
| EP-1972330-A2 | Cosmetic or pharmaceutical compositions comprising modified polysiloxanes with at least one carbamate group | CLARIANT INTERNATIONAL LTD. (CH) | 2008-09-24 | — | — | EP | disclosed |
| US-20080009429-A1 | Cosmetic or dermatological cleansing compositions comprising secondary alkanesulfonates | CLARIANT INTERNATIONAL LTD. | 2008-01-10 | — | — | US | disclosed |
| US-20070116654-A1 | Cosmetics | SHISEIDO CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-7169379-B2 | Cosmetics | SHISEIDO CO., LTD. (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-1352638-A1 | COSMETICS | SHISEIDO COMPANY, LTD. (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-20030185772-A1 | Cosmetics | SHISEIDO COMPANY, LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308224-A1 | COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS COMPRISING ISOSORBIDE DIESTERS AND UV FILTERS | POLR1C, CUTA, DEGS1 | KDM4E 3814/4885HTT 2580/4885SMPD1 385/4885 |
| US-20100260696-A1 | Aqueous Compositions Containing Alkoxylated Phosphoric Acid Triesters | HAO2, HAO1, ALOX15B | KDM4E 3889/4885HTT 3687/4885SMPD1 1103/4885 |
| US-20140348763-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP | ADH5, ADH1A, ADH1C | KDM4E 3610/4885HTT 4773/4885SMPD1 1002/4885 |
| US-20160000080-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALIPHATIC VICINAL DIOLS | HSD17B12, DHCR7, ERG28 | KDM4E 4618/4885HTT 4883/4885SMPD1 495/4885 |
| US-20150342856-A1 | Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations | C9, PARN, SGMS1 | KDM4E 2154/4885HTT 2764/4885SMPD1 627/4885 |
| US-10406135-B2 | Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group | ADH5, ADH1A, ADH1C | KDM4E 3610/4885HTT 4773/4885SMPD1 1002/4885 |
| US-20140343171-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTER AND N-HYDROXYPYRIDONES | HSD17B3, HSD3B1, HSD3B2 | KDM4E 3919/4885HTT 1356/4885SMPD1 1639/4885 |
| US-20140369943-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE COMPOUNDS | FASN, HSD17B12, ELOVL3 | KDM4E 4637/4885HTT 4685/4885SMPD1 1120/4885 |
| US-20080009429-A1 | Cosmetic or dermatological cleansing compositions comprising secondary alkanesulfonates | SMURF1, SMURF2, CUTA | KDM4E 2230/4885HTT 917/4885SMPD1 32/4885 |
| US-20140329870-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES | HSD17B12, COASY, UGT2B17 | KDM4E 4368/4885HTT 4827/4885SMPD1 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.