Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.59 |
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4368353 | 1.00 | FPR2 (0.62) | FPR2CTSLCTSKITGB3ITGA2B | |
| SCHEMBL479010 | 0.88 | TACR1 (0.68) | CTSLCTSKITGB3ITGA2BTACR1 | |
| SCHEMBL220648 | 0.88 | TACR1 (0.68) | CTSLCTSKITGB3ITGA2BTACR1 | |
| SCHEMBL7372270 | 0.88 | TACR1 (0.68) | CTSLCTSKITGB3ITGA2BTACR1 | |
| SCHEMBL219151 | 0.88 | TACR1 (0.68) | CTSLCTSKITGB3ITGA2BTACR1 | |
| SCHEMBL26661077 | 0.88 | TACR1 (0.68) | CTSLCTSKITGB3ITGA2BTACR1 | |
| SCHEMBL1795688 | 0.88 | TGM2 (0.60) | FPR2CTSLCTSKITGB3ITGA2B | |
| SCHEMBL19401964 | 0.88 | ITGB3 (0.65) | CTSLCTSKITGB3ITGA2BTACR1 | |
| SCHEMBL14485683 | 0.86 | ITGB3 (0.67) | ITGB3ITGA2BITGAVGPR34 | |
| SCHEMBL14485681 | 0.86 | ITGB3 (0.67) | ITGB3ITGA2BITGAVGPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| CN-101267813-A | Substituted propanamide derivative and pharmaceutical composition containing the same | DAIICHI SANKYO CO LTD (JP) | 2008-09-17 | — | — | CN | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |