Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979300 | 0.87 | CDK2 (0.36) | RORCCYP2C9MEN1ALDH1A1KMT2A | |
| SCHEMBL3995880 | 0.85 | NTRK1 (0.33) | NTRK1PCSK9 | |
| SCHEMBL3989803 | 0.84 | ABCG2 (0.39) | RORCMEN1ALDH1A1KMT2ACNR2 | |
| SCHEMBL4257168 | 0.82 | POLB (0.33) | ALDH1A1KMT2APOLBCYP2C19MAOB | |
| SCHEMBL3994459 | 0.81 | PCSK9 (0.51) | RORCCYP3A4CYP2C9CNR1CNR2 | |
| SCHEMBL4259652 | 0.81 | NR4A2 (0.34) | RORCMEN1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL3972624 | 0.81 | POLB (0.55) | MEN1ALDH1A1KMT2APOLBMAOB | |
| SCHEMBL1742839 | 0.79 | CES2 (0.46) | ALDH1A1 | |
| SCHEMBL3973248 | 0.78 | KDM4E (0.42) | RORCALDH1A1CNR1CNR2POLB | |
| SCHEMBL3978572 | 0.78 | PCSK9 (0.40) | RORCMEN1ALDH1A1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |