Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257168 | 0.90 | POLB (0.33) | NR4A2MAOBCYP1A2PKMCYP2C19 | |
| SCHEMBL3989803 | 0.89 | ABCG2 (0.39) | NR4A2HPGDABCG2ESRRAALDH1A1 | |
| SCHEMBL4257184 | 0.84 | PCSK9 (0.36) | NR4A2HPGDKDM4EHSD17B10MAOB | |
| SCHEMBL3979300 | 0.82 | CDK2 (0.36) | HSD17B10MAOBCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3988367 | 0.81 | RORC (0.40) | MAOBCYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL3989840 | 0.78 | MTNR1A (0.39) | NR4A2ABCG2 | |
| SCHEMBL3990318 | 0.78 | NR4A2 (0.35) | NR4A2HPGDKDM4EABCG2ALDH1A1 | |
| SCHEMBL3972624 | 0.76 | POLB (0.55) | NR4A2MAOBALDH1A1MAPTMEN1 | |
| SCHEMBL3993826 | 0.74 | RORC (0.42) | HPGDKDM4EHSD17B10ABCG2ESRRA | |
| SCHEMBL13884875 | 0.72 | NR4A2 (0.42) | NR4A2KDM4ECYP1A2PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |