Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819293 | 0.71 | CTSC (0.46) | — | |
| SCHEMBL2819297 | 0.71 | CTSC (0.46) | — | |
| SCHEMBL3988449 | 0.66 | CTSC (0.39) | P2RX7 | |
| SCHEMBL4664168 | 0.61 | P2RX7 (0.50) | P2RX7ADORA2AMAOB | |
| SCHEMBL31645933 | 0.60 | MAOB (0.55) | P2RX7ADORA2AMAOB | |
| SCHEMBL2312720 | 0.60 | MAOB (0.55) | P2RX7ADORA2AMAOB | |
| SCHEMBL27968696 | 0.60 | P2RX7 (0.40) | P2RX7MAOB | |
| SCHEMBL19837388 | 0.59 | P2RX7 (0.47) | P2RX7ADORA2AMAOB | |
| SCHEMBL868879 | 0.59 | P2RX7 (0.50) | P2RX7ADORA2AMAOB | |
| SCHEMBL29755971 | 0.59 | P2RX7 (0.50) | P2RX7ADORA2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547701-B2 | Haloalkyl containing compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-20050182096-A1 | Haloalkyl containing compounds as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182096-A1 | Haloalkyl containing compounds as cysteine protease inhibitors | CTSF, CTSS, CTSE | P2RX7 3287/4885ADORA2A 4547/4885MAOB 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.