Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879302 | 0.80 | ANPEP (0.52) | POLBANPEPGAAMEN1KMT2A | |
| SCHEMBL3989338 | 0.80 | MMP1 (0.41) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9602121 | 0.78 | ANPEP (0.58) | POLBANPEPGAAALDH1A1MEN1 | |
| SCHEMBL9590000 | 0.78 | ANPEP (0.58) | POLBANPEPGAAALDH1A1MEN1 | |
| SCHEMBL3991380 | 0.78 | SCN9A (0.36) | GAAMEN1KMT2ATDP1MMP1 | |
| SCHEMBL13796803 | 0.78 | SCN9A (0.36) | GAAMEN1KMT2ATDP1MMP1 | |
| SCHEMBL7879201 | 0.77 | DHODH (0.49) | POLBANPEPGAAALDH1A1MEN1 | |
| SCHEMBL7873337 | 0.77 | KMT2A (0.61) | POLBANPEPGAAMEN1KMT2A | |
| SCHEMBL18194421 | 0.76 | ALOX15 (0.51) | POLBGAAALDH1A1MEN1KMT2A | |
| SCHEMBL14856009 | 0.74 | SLC7A5 (0.67) | POLBALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |