Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735020 | 0.76 | KIF11 (0.56) | TSHRKIF11CYP1A2MAPK1KCNN4 | |
| SCHEMBL7201481 | 0.73 | TSHR (0.50) | TSHRKIF11CYP1A2MAPK1KCNN4 | |
| SCHEMBL29090083 | 0.73 | MAPK1 (0.44) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL3986290 | 0.73 | TSHR (0.44) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL11778635 | 0.72 | CHRM2 (0.41) | TSHRMAPK1KCNN4ALDH1A1TAAR1 | |
| SCHEMBL995346 | 0.72 | TSHR (0.55) | TSHRKIF11CYP1A2MAPK1KCNN4 | |
| SCHEMBL547587 | 0.72 | TSHR (0.55) | TSHRKIF11CYP1A2MAPK1KCNN4 | |
| SCHEMBL8588185 | 0.69 | CHRM2 (0.53) | TSHRCYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1224334 | 0.69 | TSHR (0.50) | TSHRKIF11CYP1A2MAPK1KCNN4 | |
| SCHEMBL10707751 | 0.69 | TSHR (0.50) | TSHRCYP1A2MAPK1KCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061789-A2 | THIADIAZOLE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008032858-A2 | THIADIAZOLE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-03-20 | — | — | WO | disclosed |