Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268267 | 0.77 | ALDH1A1 (0.44) | TSHRALDH1A1KIF11PTPN1MAPK1 | |
| SCHEMBL5735020 | 0.76 | KIF11 (0.56) | TSHRALDH1A1KIF11MAPK1KCNN4 | |
| SCHEMBL29090083 | 0.73 | MAPK1 (0.44) | TSHRALDH1A1KIF11MAPK1KCNN4 | |
| SCHEMBL3988998 | 0.73 | TSHR (0.44) | TSHRALDH1A1KIF11MAPK1KCNN4 | |
| SCHEMBL2867593 | 0.72 | TSHR (0.55) | TSHRALDH1A1KIF11PTPN1MAPK1 | |
| SCHEMBL28318379 | 0.70 | LTA4H (0.44) | TSHRALDH1A1KIF11PTPN1MAPK1 | |
| SCHEMBL6988143 | 0.69 | TSHR (0.50) | TSHRALDH1A1KIF11PTPN1MAPK1 | |
| SCHEMBL914885 | 0.69 | ALDH1A1 (0.50) | TSHRALDH1A1KIF11PTPN1MAPK1 | |
| SCHEMBL17763368 | 0.69 | TSHR (0.50) | TSHRALDH1A1KIF11PTPN1MAPK1 | |
| SCHEMBL8589920 | 0.67 | TSHR (0.48) | TSHRALDH1A1KIF11PTPN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061789-A2 | THIADIAZOLE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008032858-A2 | THIADIAZOLE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-03-20 | — | — | WO | disclosed |