Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987590 | 0.90 | MAOB (0.33) | TRPA1OPRD1OPRK1REN | |
| SCHEMBL3986378 | 0.88 | FCER2 (0.30) | REN | |
| SCHEMBL3995150 | 0.83 | CYP3A4 (0.35) | TRPA1OPRD1OPRM1REN | |
| SCHEMBL3989091 | 0.82 | REN (0.34) | OPRD1OPRK1OPRM1REN | |
| SCHEMBL3987434 | 0.81 | ALOX15 (0.32) | TRPA1OPRD1OPRK1OPRM1 | |
| SCHEMBL3989149 | 0.81 | BACE1 (0.36) | OPRD1OPRK1REN | |
| SCHEMBL3990161 | 0.79 | F2R (0.30) | — | |
| SCHEMBL3993021 | 0.75 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL3994857 | 0.75 | ACACB (0.33) | OPRD1OPRK1OPRM1REN | |
| SCHEMBL13795944 | 0.75 | SLC7A5 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |