Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.32 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3995150 | 0.94 | CYP3A4 (0.35) | BACE1RENFCER2MC4RMC3R | |
| SCHEMBL3989091 | 0.91 | REN (0.34) | RENROCK2ROCK1FCER2OPRK1 | |
| SCHEMBL3987590 | 0.83 | MAOB (0.33) | RENOPRK1OPRD1 | |
| SCHEMBL3994857 | 0.82 | ACACB (0.33) | RENROCK2ROCK1FCER2OPRK1 | |
| SCHEMBL3989034 | 0.81 | TRPA1 (0.33) | RENOPRK1OPRD1 | |
| SCHEMBL3986378 | 0.81 | FCER2 (0.30) | RENFCER2 | |
| SCHEMBL13796438 | 0.80 | MC4R (0.37) | BACE1RENMC4RMC3RMME | |
| SCHEMBL13796434 | 0.79 | MC4R (0.36) | BACE1RENFCER2MC4RMC3R | |
| SCHEMBL3989491 | 0.77 | MC4R (0.35) | RENFCER2MC4RMC3ROPRK1 | |
| SCHEMBL3989661 | 0.77 | BACE1 (0.34) | BACE1RENMC4RMC3RBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |