Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985312 | 0.90 | TDP1 (0.47) | KDM4EALDH1A1HPGDPKMPTGDR | |
| SCHEMBL3984323 | 0.85 | LMNA (0.43) | LMNAKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL3985878 | 0.84 | PTGDR (0.51) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL3981435 | 0.81 | PKM (0.46) | LMNAKDM4EALDH1A1PKMPTGDR | |
| SCHEMBL3778420 | 0.78 | KDM4E (0.43) | LMNAKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL3981440 | 0.78 | MEN1 (0.38) | HPGDKMT2AMAPTHIF1APARP1 | |
| SCHEMBL3779603 | 0.76 | KDM4E (0.39) | LMNAKDM4EALDH1A1HPGDPKM | |
| SCHEMBL3979381 | 0.76 | LMNA (0.48) | LMNAKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL3980996 | 0.74 | PTGDR2 (0.39) | LMNAKDM4EALDH1A1MAPK1PKM | |
| SCHEMBL3989929 | 0.73 | KDM4E (0.52) | LMNAKDM4EALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |