Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.30 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.30 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16341708 | 0.59 | ALDH1A1 (0.42) | COMTALDH1A1LRRK2PIK3CDPIK3CA | |
| SCHEMBL26195687 | 0.57 | COMT (0.41) | COMTALDH1A1LRRK2SMN1; SMN2 | |
| SCHEMBL16341650 | 0.57 | COMT (0.41) | COMTALDH1A1LRRK2PIK3CDSMN1; SMN2 | |
| SCHEMBL14996594 | 0.57 | SMN1; SMN2 (0.51) | COMTALDH1A1LRRK2SMN1; SMN2KDM4E | |
| SCHEMBL3761896 | 0.57 | COMT (0.49) | COMTALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL32683341 | 0.57 | ALDH1A1 (0.40) | COMTALDH1A1LRRK2PIK3CDPIK3CB | |
| SCHEMBL30143564 | 0.56 | COMT (0.41) | COMTALDH1A1LRRK2SMN1; SMN2KDM4E | |
| SCHEMBL26066818 | 0.56 | COMT (0.40) | COMTALDH1A1LRRK2SMN1; SMN2HPGD | |
| SCHEMBL31192195 | 0.56 | NOTUM (0.42) | COMTALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL20187336 | 0.56 | COMT (0.40) | COMTALDH1A1LRRK2SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557067-B2 | Pyrazole sulfonylurea compound and herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20080064600-A1 | Pyrazole Sulfonylurea Compound and Herbicide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064600-A1 | Pyrazole Sulfonylurea Compound and Herbicide | GLP1R, MSRB3, PDXK | COMT 2999/4885ALDH1A1 893/4885LRRK2 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.