Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 11/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989532 | 0.84 | HSD17B10 (0.36) | ROCK2ALOX15HSD17B10KDM4ERECQL | |
| SCHEMBL3988348 | 0.77 | PTPRB (0.32) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL3994642 | 0.70 | TAAR1 (0.52) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL18194421 | 0.69 | ALOX15 (0.51) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL14856009 | 0.68 | SLC7A5 (0.67) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL10656842 | 0.68 | SLC7A5 (0.67) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL7892985 | 0.68 | SLC7A5 (0.67) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL3985975 | 0.68 | ALDH1A1 (0.43) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL3985972 | 0.68 | ALOX15 (0.43) | ALOX15HSD17B10KDM4ERECQLHIF1A | |
| SCHEMBL29809967 | 0.68 | SLC7A5 (0.67) | ALOX15HSD17B10KDM4ERECQLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |