Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989527 | 0.84 | ROCK2 (0.34) | HSD17B10KDM4EHPGDMAPK1POLB | |
| SCHEMBL3988353 | 0.77 | MMP13 (0.36) | KDM4EMAPK1GAAHDAC6POLB | |
| SCHEMBL3994642 | 0.70 | TAAR1 (0.52) | HSD17B10KDM4EHPGDMAPK1POLB | |
| SCHEMBL18194421 | 0.69 | ALOX15 (0.51) | HSD17B10KDM4EHPGDMAPK1GAA | |
| SCHEMBL10656842 | 0.68 | SLC7A5 (0.67) | HSD17B10KDM4EHPGDPOLBHSP90AA1 | |
| SCHEMBL7892985 | 0.68 | SLC7A5 (0.67) | HSD17B10KDM4EHPGDPOLBHSP90AA1 | |
| SCHEMBL14856009 | 0.68 | SLC7A5 (0.67) | HSD17B10KDM4EHPGDPOLBHSP90AA1 | |
| SCHEMBL3985975 | 0.68 | ALDH1A1 (0.43) | HSD17B10KDM4EHPGDMAPK1GAA | |
| SCHEMBL3985970 | 0.68 | ALOX15 (0.43) | HSD17B10KDM4EHPGDMAPK1GAA | |
| SCHEMBL29809967 | 0.68 | SLC7A5 (0.67) | HSD17B10KDM4EHPGDPOLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |