Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | MRE11 | P49959 | 2/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988353 | 0.88 | MMP13 (0.36) | PTPRBSCN10AKDM4EMAPK1LMNA | |
| SCHEMBL3993261 | 0.84 | PSMB11 (0.34) | CYP3A4NR1I2NR3C1CYP1A2CYP2D6 | |
| SCHEMBL3987600 | 0.78 | — | — | |
| SCHEMBL4657375 | 0.77 | ACACB (0.38) | ALOX15ALOX12KDM4EMEN1ALDH1A1 | |
| SCHEMBL3989527 | 0.77 | ROCK2 (0.34) | SCN10AALOX15ALOX12KDM4EMEN1 | |
| SCHEMBL3987548 | 0.75 | ERCC1 (0.30) | — | |
| SCHEMBL3986499 | 0.75 | PTPRB (0.40) | PTPRBMRE11ALOX15ALOX12TP53 | |
| SCHEMBL3994576 | 0.73 | ROCK2 (0.30) | — | |
| SCHEMBL3993264 | 0.72 | MAPT (0.36) | CYP3A4NR1I2NR3C1CYP1A2POLB | |
| SCHEMBL3988356 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |