Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819910 | 1.00 | KMT2A (0.43) | KMT2AOPRM1OPRL1HTR2CSLC6A9 | |
| SCHEMBL3990516 | 1.00 | KMT2A (0.43) | KMT2AOPRM1OPRL1HTR2CSLC6A9 | |
| SCHEMBL3820386 | 1.00 | KMT2A (0.43) | KMT2AOPRM1OPRL1HTR2CSLC6A9 | |
| SCHEMBL3992857 | 0.99 | KMT2A (0.43) | KMT2AOPRM1OPRL1HTR2CSLC6A9 | |
| SCHEMBL3824513 | 0.96 | KMT2A (0.43) | KMT2AOPRM1OPRL1HTR2COPRD1 | |
| SCHEMBL3990437 | 0.94 | KMT2A (0.44) | KMT2AOPRM1OPRL1HTR2CSLC6A9 | |
| SCHEMBL3443526 | 0.91 | KMT2A (0.40) | KMT2AOPRM1OPRL1HTR2CSLC6A9 | |
| SCHEMBL3446137 | 0.90 | KMT2A (0.41) | KMT2AOPRM1OPRL1HTR2CSLC6A9 | |
| SCHEMBL3992418 | 0.86 | OPRM1 (0.42) | KMT2AOPRM1OPRL1SLC6A9SLC6A5 | |
| SCHEMBL3991452 | 0.86 | OPRM1 (0.58) | KMT2AOPRM1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507816-B2 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | GRUENENTHAL GMBH (DE) | 2009-03-24 | — | — | US | claimed |
| US-20050020691-A1 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | GRUENENTHAL GMBH (DE) | 2005-01-27 | — | — | US | claimed |
| US-7507816-B2 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | GRUENENTHAL GMBH (DE) | 2009-03-24 | — | — | US | disclosed |
| US-20050020691-A1 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | GRUENENTHAL GMBH (DE) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020691-A1 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | ADRB1, ADRB2, ADRA1D | KMT2A 2324/4885OPRM1 36/4885OPRL1 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.