Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996013 | 0.90 | KDR (0.41) | POLBMITFALDH1A1LMNAMAPT | |
| SCHEMBL3992947 | 0.90 | POLB (0.38) | POLBMITFALDH1A1LMNAMAPT | |
| SCHEMBL3978572 | 0.88 | PCSK9 (0.40) | POLBMITFALDH1A1LMNAMAPT | |
| SCHEMBL3997478 | 0.88 | POLB (0.36) | POLBMITFALDH1A1LMNAMAPT | |
| SCHEMBL3972624 | 0.86 | POLB (0.55) | POLBMITFALDH1A1LMNAMAPT | |
| SCHEMBL3995936 | 0.86 | ALDH1A1 (0.44) | POLBALDH1A1CNR2KDM4CSCN9A | |
| SCHEMBL4293828 | 0.86 | CNR1 (0.36) | POLBMAPTKMT2ACNR1CNR2 | |
| SCHEMBL3990286 | 0.85 | SCN9A (0.40) | POLBCNR1CNR2SCN9AHTT | |
| SCHEMBL3990318 | 0.82 | NR4A2 (0.35) | POLBALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL3973248 | 0.81 | KDM4E (0.42) | POLBALDH1A1CNR1CNR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |