Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992947 | 0.86 | POLB (0.38) | CNR1CNR2NTRK1POLBMEN1 | |
| SCHEMBL3992240 | 0.86 | POLB (0.38) | CNR1CNR2IMPDH2NTRK1POLB | |
| SCHEMBL3997478 | 0.84 | POLB (0.36) | CNR1CNR2POLBMEN1MAPT | |
| SCHEMBL3978572 | 0.84 | PCSK9 (0.40) | CNR1CNR2NTRK1POLBMEN1 | |
| SCHEMBL3972624 | 0.82 | POLB (0.55) | POLBMEN1MAPTKMT2A | |
| SCHEMBL3995936 | 0.82 | ALDH1A1 (0.44) | CNR2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3990286 | 0.81 | SCN9A (0.40) | CNR1CNR2NTRK1POLBSCN9A | |
| SCHEMBL3996013 | 0.79 | KDR (0.41) | CNR1CNR2POLBMEN1MAPT | |
| SCHEMBL3990318 | 0.78 | NR4A2 (0.35) | CNR2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3973248 | 0.77 | KDM4E (0.42) | CNR1CNR2NTRK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |