Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9311376 | 0.98 | PTGS2 (0.67) | PTGS2ALDH1A1HSD17B10DRD1PTGS1 | |
| SCHEMBL3491279 | 0.85 | PTGS2 (0.59) | PTGS2DRD1PTGS1JAK2 | |
| SCHEMBL8487915 | 0.85 | PTGS2 (0.75) | PTGS2DRD1PTGS1 | |
| SCHEMBL1271133 | 0.84 | ALDH1A1 (0.58) | PTGS2ALDH1A1HSD17B10PTGS1 | |
| SCHEMBL4861820 | 0.82 | CA2 (0.65) | PTGS2ALDH1A1HSD17B10DRD1PTGS1 | |
| SCHEMBL5502727 | 0.82 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL18342129 | 0.81 | ALDH1A1 (0.65) | PTGS2ALDH1A1HSD17B10PTGS1 | |
| SCHEMBL10826584 | 0.81 | ALDH1A1 (0.54) | PTGS2ALDH1A1HSD17B10PTGS1 | |
| SCHEMBL9311607 | 0.80 | JAK2 (0.53) | PTGS2ALDH1A1HSD17B10JAK2 | |
| SCHEMBL758098 | 0.80 | CA12 (0.49) | PTGS2ALDH1A1HSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114340374-B | Sowing device and method for treating seeds during planting | 先正达参股股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-108463460-B | Microbiocidal oxadiazole derivatives | 先正达参股股份有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-109195966-B | Microbiocidal thiazole derivatives | 先正达参股股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-108430980-B | Microbicidal oxadiazole derivatives | 先正达参股股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114340374-A | Sowing device and method for treating seeds during planting | 先正达参股股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108137517-B | Microbicidal oxadiazole derivatives | 先正达参股股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114269143-A | High precision greenhouse treatment of seeds and seedlings | 先正达参股股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269144-A | Precision processing and sowing or planting method and apparatus | 先正达参股股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269145-A | Apparatus and method for converting an existing sowing apparatus | 先正达参股股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114258261-A | Apparatus and method for reducing dust development in precision drilling | 先正达参股股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |
| US-20090298876-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-12-03 | — | — | US | disclosed |
| US-20090246820-A1 | COMPOUNDS USEFUL IN CFTR ASSAYS AND METHODS THEREWITH | VERTEX PHARMACEUTICALS INCORPORATED | 2009-10-01 | — | — | US | disclosed |
| US-20090227797-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-09-10 | — | — | US | disclosed |
| US-7495103-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-03-20 | — | — | US | disclosed |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2006-04-06 | — | — | US | disclosed |
| EP-0536151-B1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | BOOTS CO PLC (GB) | 1994-09-14 | — | — | EP | disclosed |
| US-5302720-A | Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents | THE BOOTS COMPANY (GB) | 1994-04-12 | — | — | US | disclosed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227797-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | PTGS2 1409/4885ALDH1A1 2165/4885HSD17B10 1468/4885 |
| US-20090298876-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | PTGS2 1409/4885ALDH1A1 2165/4885HSD17B10 1468/4885 |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | CFTR, ABCB1, ABCC1 | PTGS2 1280/4885ALDH1A1 2651/4885HSD17B10 1678/4885 |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | CFTR, ABCC4, ABCC2 | PTGS2 1235/4885ALDH1A1 2221/4885HSD17B10 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.