SCHEMBL4000348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3999412	0.89	GSK3B (0.52)	ADORA2AALDH1A1MAPTHTTNPSR1
	SCHEMBL3996832	0.88	ADORA2A (0.56)	MAOBADORA2AALDH1A1MAPTHTT
	SCHEMBL3999451	0.88	ADORA2A (0.46)	MAOBADORA2AALDH1A1MAPTHTT
	SCHEMBL4005546	0.85	ROCK2 (0.42)	MAOBADORA2AALDH1A1MAPTHTT
	SCHEMBL5904466	0.85	HRH3 (0.43)	MAOBADORA2AALDH1A1MAPTHTT
	SCHEMBL3997023	0.84	GSK3B (0.43)	ADORA2AGSK3BHRH3
	SCHEMBL3998490	0.83	GSK3B (0.46)	MAOBADORA2AALDH1A1NPSR1GSK3B
	SCHEMBL6654588	0.82	GSK3B (0.41)	MAOBADORA2AALDH1A1MAPTHTT
	SCHEMBL4001235	0.82	GSK3B (0.55)	ADORA2AALDH1A1MAPTHTTNPSR1
	SCHEMBL3998481	0.82	DRD2 (0.44)	GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.