Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997189 | 0.87 | MAPT (0.46) | ALDH1A1KMT2ACYP2C8TSHR | |
| SCHEMBL4004650 | 0.86 | USP2 (0.44) | ALDH1A1KMT2ACYP2C8TSHRACHE | |
| SCHEMBL4002003 | 0.85 | CYP2C8 (0.46) | ALDH1A1KMT2ACYP2C8TSHRACHE | |
| SCHEMBL4004759 | 0.84 | CYP2C8 (0.45) | ALDH1A1KMT2ACYP2C8TSHRACHE | |
| SCHEMBL4002142 | 0.81 | KMT2A (0.44) | ALDH1A1ALOX12KMT2ATSHRACHE | |
| SCHEMBL4008320 | 0.79 | LMNA (0.42) | ALDH1A1KMT2ATSHRACHE | |
| SCHEMBL4002683 | 0.79 | ACHE (0.44) | ALDH1A1KMT2AACHE | |
| SCHEMBL17667812 | 0.79 | CYP2C8 (0.59) | ALDH1A1ALOX12KMT2ACYP2C8TSHR | |
| SCHEMBL3008308 | 0.77 | ALDH1A1 (0.58) | ALDH1A1ALOX12KMT2ACYP2C8 | |
| SCHEMBL3008253 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ALOX12KMT2ACYP2C8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |